United Space Alliance, my employer, is NASA's prime contractor for Space Shuttle and ISS operations.
Johnson Space Center in Houston, where I work.
Space Operations Computing (SpOC) applications are displayed at
Space.com, a great site with lots of space news and links
J-Track 3D, from Marshall Space Flight Center, my favorite Satellite, Shuttle, and Space Station tracker.
Check out NASA's SkyWatch page to find out when you can see the station fly overhead.
NASA TV - we get this channel on cable in Houston. Check it out in RealVideo format here! Also, there's NASA TV Florida and a Live Processing Video Feed from KSC, too!
NASA's International Space Station Tracking Page
For information on the current (or next) Shuttle mission, go to http://science.ksc.nasa.gov/shuttle/countdown/
To see the Station's and Shuttle's current location(s), check out the NASA's Live Tracking Monitor